Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.
Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.

Nationwide, there are over 125,000 new cases and approximately 50,000 deaths each year. The incidence rate of new cases has decreased significantly due to several factors like earlier screening and detection. As a result of this and improved treatment options, the death rate from colorectal cancer in the United States has decreased by about 25%.
Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.
Breast Vernon CC et al. and van der Zee et al., Int. J. Radiation Oncology Biol. Phys. 1996; 35(4) 731-744 Head & Neck Valdagni et al., Int. J. Radiation Oncology Biol. Phys. 1994; 28: 163-169 Melanoma Overgaard J et al., Int. J. Hyperthermia 1996; 12(1): 3-20 Cervical van der Zee et al. Int. J. Hyperthermia 2002; 18(1): 1-12, Berdov, BA and Menteshashvili, GZ. Thermoradiotherapy of patients with locally advanced carcinoma of the rectum. Int. J. Hyperthermia 1990; 6(5): 881-890
Cancer of the large bowel is collectively called colorectal cancer, and includes cancer of the colon, rectum and anus. Most colorectal cancers arise from polyps, specifically adenomatous polyps. A polyp is a mass of abnormal cells on the surface of the colon or rectum. Polyps can be classified as non-cancerous such as neoplastic hamartoma, a hyperplastic polyp, or an adenomatous polyp.
Up to 25% of patients with colorectal cancer have a family history of the disease, suggesting a hereditary predisposition. Other factors like diet, smoking, and diseases like inflammatory bowel disease increases the risk of developing colorectal cancer.
Depending on the location of the tumor, symptoms can vary from abdominal pain, chronic slow blood loss that cannot be seen with the naked eye, more rapid and obvious blood loss, or obstruction or inability to pass stools.
Our colon & rectal cancer treatment in Irvine can be combined with surgery, chemotherapy, radiation therapy, and newer biologic targeted therapy. Like so many other cancers, the initial stage correlates strongly with the risk of recurrence, as well as the choice and outcome of treatments. The earlier colorectal cancer is diagnosed, the more likely it can be cured.
to Treat Colon & Rectal Cancer
Hyperthermia uses targeted ultrasonic heat to disrupt cancer cell membranes and increases blood flow to the tumor. This increased blood flow makes the tumor more sensitive and vulnerable to both the body’s natural immune defenses and to other cancer therapies like radiation therapy and chemotherapy.
“My mom received hyperthermia here in conjunction with five rounds of chemotherapy for her stage four lung cancer. She saw a reduction in tumor burden by over 50% and her cancer stabilized.The team at HCI is thoughtful and caring – I recommend hyperthermia for all cancer patients undergoing chemo or radiation.”
“I just wanted to let you know that I am in my first cancer-free year! Thank you again for the time, effort and care given to me during my time of need. I will continue to spread the word of incredible hyperthermia treatments to those in need.”
– Merry Chase
“The hyperthermia treatments were the major difference in treating my cancer. I am forever grateful for this technology.”
– Carla Olson
The team at HCI is outstanding. They treated us with so much care and respect! The technology helped my wife tremendously and the treatment is relatively comfortable compared to many cancer therapies. We highly recommend. Oh, and it is in one of the most beautiful places on the planet!
I went to Hyperthermia cancer institute 5-6 days a week for 4 weeks. On my birthday, I received a call from my oncologist and they could not find a trace of tumor in the MRI. The tumor went to a zero! It is a complete success.
Dr. Pinzone and the whole team are fantastic and truly care about their patients. I highly recommend!
My mom received hyperthermia here in conjunction with five rounds of chemotherapy for her stage four lung cancer. She saw a reduction in tumor burden by over 50% and her cancer stabilized. I recommend hyperthermia for all cancer patients undergoing chemo or radiation.
The team at HCI is outstanding. They treated us with so much care and respect! The technology helped my wife tremendously and the treatment is relatively comfortable compared to many cancer therapies. We highly recommend. Oh, and it is in one of the most beautiful places on the planet!
I went to Hyperthermia cancer institute 5-6 days a week for 4 weeks. On my birthday, I received a call from my oncologist and they could not find a trace of tumor in the MRI. The tumor went to a zero! It is a complete success.
Dr. Pinzone and the whole team are fantastic and truly care about their patients. I highly recommend!
Hyperthermia treatment is non-invasive and non-toxic. There is no damage to normal healthy tissues during your session, meaning it can maximize the efficacy of other treatments like radiation and chemo without risking damage to vital organs. Most patients find it easy to tolerate and do not experience side effects.
While hyperthermia is most commonly paired with radiation or chemotherapy, it can also enhance outcomes when used in conjunction with surgery, especially for addressing residual cancer cells post-surgery. Your doctor will advise if this combination is suitable for your case.