Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.
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Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.
Nationwide, there are over 125,000 new cases and approximately 50,000 deaths each year. The incidence rate of new cases has decreased significantly due to several factors like earlier screening and detection. As a result of this and improved treatment options, the death rate from colorectal cancer in the United States has decreased by about 25%.
Cancer of the large bowel is collectively called colorectal cancer, and includes cancer of the colon, rectum and anus. Most colorectal cancers arise from polyps, specifically adenomatous polyps. A polyp is a mass of abnormal cells on the surface of the colon or rectum. Polyps can be classified as non-cancerous such as neoplastic hamartoma, a hyperplastic polyp, or an adenomatous polyp.
Up to 25% of patients with colorectal cancer have a family history of the disease, suggesting a hereditary predisposition. Other factors like diet, smoking, and diseases like inflammatory bowel disease increases the risk of developing colorectal cancer.
Depending on the location of the tumor, symptoms can vary from abdominal pain, chronic slow blood loss that cannot be seen with the naked eye, more rapid and obvious blood loss, or obstruction or inability to pass stools.
Our colon & rectal cancer treatment in Irvine can be combined with surgery, chemotherapy, radiation therapy, and newer biologic targeted therapy. Like so many other cancers, the initial stage correlates strongly with the risk of recurrence, as well as the choice and outcome of treatments. The earlier colorectal cancer is diagnosed, the more likely it can be cured.
to Treat Colon & Rectal Cancer
Hyperthermia uses targeted ultrasonic heat to disrupt cancer cell membranes and increases blood flow to the tumor. This increased blood flow makes the tumor more sensitive and vulnerable to both the body’s natural immune defenses and to other cancer therapies like radiation therapy and chemotherapy.
Our cancer center in Irvine understands that researching cancer treatment can be daunting. Below is a selection of studies from trusted sources that can help you gain a better understanding of how hyperthermia can aid treatment for colorectal cancer.
Overall survival rate at 5 years post-treatment of rectal cancer increased with the addition of hyperthermia.
Breast Vernon CC et al. and van der Zee et al., Int. J. Radiation Oncology Biol. Phys. 1996; 35(4) 731-744 Head & Neck Valdagni et al., Int. J. Radiation Oncology Biol. Phys. 1994; 28: 163-169 Melanoma Overgaard J et al., Int. J. Hyperthermia 1996; 12(1): 3-20 Cervical van der Zee et al. Int. J. Hyperthermia 2002; 18(1): 1-12, Berdov, BA and Menteshashvili, GZ. Thermoradiotherapy of patients with locally advanced carcinoma of the rectum. Int. J. Hyperthermia 1990; 6(5): 881-890