By increasing the blood flow to a tumor, hyperthermia delivers more chemotherapy to all parts of the tumor, especially to the tumor’s core where it is difficult for chemotherapy to reach. Hyperthermia also makes the out membrane of tumor cells more porous, which allows chemotherapy and other medications to better penetrate the tumor cells, further amplifying the effects of chemotherapy. Finally, many types of chemotherapy damage the DNA of cancer cells, targeting them for destruction. Hyperthermia works by preventing your body from repairing the cancer cell DNA, thereby keeping the cancer cell vulnerable to chemotherapy.